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The Role of Genetic Testing for Inherited Prostate Cancer Risk

Written By Grand Rounds in Urology on Wednesday, Feb 07, 2018 | 05:36 PM

 
Dr. Veda N. Giri, MD, commenced the Philadelphia Prostate Cancer Consensus 2017 by explaining the purpose and need for creating updated, centralized guidelines regarding genetic testing for inherited prostate cancer. She summarizes the scientific research advances since 1999 which prove the link between genetic mutations, especially BRCA and BRCA2. Also, researchers identified HOXB13 as the first hereditary prostate cancer gene. Then, Dr. Vera relates these scientific advances to a rise in clinical capabilities, such as next generation sequencing technology and prostate cancer multigene panel testing.